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JAMA. 2015 Aug 18;314(7):720-1. doi: 10.1001/jama.2015.7918.

Isotonic vs Hypotonic Intravenous Fluids for Hospitalized Children.

Author information

1
Department of General Medicine, Royal Children's Hospital, Melbourne, Australia2Murdoch Childrens Research Institute, Melbourne, Australia3Department of Pediatrics, University of Melbourne, Melbourne, Australia.

Abstract

CLINICAL QUESTION:

Is isotonic fluid associated with a lower incidence of hyponatremia when compared with hypotonic fluid for maintenance intravenous fluid therapy in children?

BOTTOM LINE:

Compared with hypotonic fluid, isotonic fluid is associated with a lower incidence of hyponatremia, without evidence of an increase in adverse outcomes.

PMID:
26284724
DOI:
10.1001/jama.2015.7918
[Indexed for MEDLINE]

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