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Int J Environ Res Public Health. 2015 Jul 31;12(8):9068-88. doi: 10.3390/ijerph120809068.

Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis.

Author information

1
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. lianhui1988@163.com.
2
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. yanping.ruan@163.com.
3
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. 18911122174@163.com.
4
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. lxlryyc@sina.com.
5
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. Fan@pumch.cn.

Abstract

BACKGROUND AND PURPOSE:

The relationship between stroke and short-term temperature changes remains controversial. Therefore, we conducted a systematic review and meta-analysis to investigate the association between stroke and both high and low temperatures, and health assessment.

METHODS:

We searched PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI) and Wanfang Data up to 14 September 2014. Study selection, quality assessment, and author-contractions were steps before data extraction. We converted all estimates effects into relative risk (RR) per 1 °C increase/decrease in temperature from 75th to 99th or 25th to 1st percentiles, then conducted meta-analyses to combine the ultimate RRs, and assessed health impact among the population.

RESULTS:

20 articles were included in the final analysis. The overall analysis showed a positive relationship between 1 °C change and the occurrence of major adverse cerebrovascular events (MACBE), 1.1% (95% confidence intervals (CI), 0.6 to 1.7) and 1.2% (95% CI, 0.8 to 1.6) increase for hot and cold effects separately. The same trends can be found in both effects of mortality and the cold effect for morbidity. Hot temperature acted as a protective factor of hemorrhage stroke (HS), -1.9% (95% CI, -2.8 to -0.9), however, it acted as a risk factor for ischemic stroke (IS), 1.2% (95% CI, 0.7 to 1.8).

CONCLUSION:

Short-term changes of both low and high temperature had statistically significant impacts on MACBE.

KEYWORDS:

meta-analysis; short-term; stroke; temperature change

PMID:
26264018
PMCID:
PMC4555265
DOI:
10.3390/ijerph120809068
[Indexed for MEDLINE]
Free PMC Article

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