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J Rheumatol. 1989 Dec;16(12):1592-6.

Cyclophosphamide treatment of interstitial pulmonary fibrosis in polymyositis/dermatomyositis.

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  • 1Rheumatic Disease Unit, Ottawa General Hospital, University of Ottawa, ON, Canada.

Abstract

Interstitial pulmonary fibrosis is a serious complication of inflammatory muscle disease associated with significant morbidity and mortality. We describe 3 consecutive cases complicating dermatomyositis (1 case, anti-Jo-1 antibody negative) and polymyositis (2 cases, anti-Jo-1 antibody positive) in which cyclophosphamide was added to prednisone therapy with favorable outcomes.

PMID:
2625692
[PubMed - indexed for MEDLINE]
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