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Anaesthesist. 2015 Aug;64(8):586-95. doi: 10.1007/s00101-015-0068-9.

[Long QT syndrome. History, genetics, clinical symptoms, causes and therapy].

[Article in German]

Author information

1
Klinik für Anästhesiologie und Operative Intensivmedizin, Klinikum Augsburg, Augsburg, Deutschland.

Abstract

The long QT syndrome is caused by a change in cardiac repolarization due to functional ion channel defects. A differentiation is made between a congenital (cLQTS) and an acquired (aLQTS) form of the disease. The disease results in the name-giving prolongation of the QT interval in the electrocardiogram and represents a predisposition for cardiac arrhythmia and sudden cardiac death. This article summarizes the current knowledge on the history, pathophysiology, clinical symptoms and therapy of cLQTS and aLQTS. This knowledge of pathophysiological features of the symptoms allows the underlying anesthesiological approach for individualized perioperative concepts for patients suffering from LQTS to be derived.

PMID:
26250931
DOI:
10.1007/s00101-015-0068-9
[Indexed for MEDLINE]

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