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Br J Sports Med. 2015 Oct;49(19):1262-7. doi: 10.1136/bjsports-2014-094306. Epub 2015 Aug 3.

Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥60 years: a systematic review and meta-analysis.

Author information

1
Department of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, PRES Lyon, Jean Monnet University, Saint-Etienne, France EA SNA EPIS 4607, Autonomic Nervous System, University of Lyon, Saint-Etienne, France EA LPE 4338, Laboratory of Exercise Physiology, University of Lyon, Saint Etienne, France.
2
Department of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, PRES Lyon, Jean Monnet University, Saint-Etienne, France EA SNA EPIS 4607, Autonomic Nervous System, University of Lyon, Saint-Etienne, France.
3
Rehabilitation Departments, University Hospital of Dijon, Dijon, France Faculty of Sport Sciences, INSERM-U1093, University of Burgundy, Dijon, France CIC INSERM 1432, Technological Platform, University Hospital of Dijon, Dijon, France.
4
Department of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, PRES Lyon, Jean Monnet University, Saint-Etienne, France EA LPE 4338, Laboratory of Exercise Physiology, University of Lyon, Saint Etienne, France.
5
Department of Public Health, Hygee Centre, Regional Centre for Cancer Prevention, Saint-Priest-en-Jarez, France CIC 1408 INSERM, Jean Monnet University, Saint-Etienne, France.
6
Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.

Abstract

BACKGROUND:

The health benefits of 150 min a week of moderate-to-vigorous-intensity physical activity (MVPA) in older adults, as currently recommended, are well established, but the suggested dose in older adults is often not reached.

OBJECTIVES:

We aimed to determine whether a lower dose of MVPA was effective in reducing mortality, in participants older than 60 years.

METHODS:

The PubMed and Embase databases were searched from inception to February 2015. Only prospective cohorts were included. Risk ratios of death were established into four doses based on weekly Metabolic Equivalent of Task (MET)-minutes, defined as inactive (reference), low (1-499), medium (500-999) or high (≥1000). Data were pooled and analysed through a random effects model using comprehensive meta-analysis software.

RESULTS:

Of the 835 reports screened, nine cohort studies remained, totalling 122 417 participants, with a mean follow-up of 9.8±2.7 years and 18 122 reported deaths (14.8%). A low dose of MVPA resulted in a 22% reduction in mortality risk (RR=0.78 (95% CI 0.71 to 0.87) p<0.0001). MVPA beyond this threshold brought further benefits, reaching a 28% reduction in all-cause mortality in older adults who followed the current recommendations (RR=0.72 (95% CI 0.65 to 0.80) p<0.0001) and a 35% reduction beyond 1000 MET-min per week (RR=0.65 (95% CI 0.61 to 0.70) p<0.0001).

CONCLUSIONS:

A dose of MVPA below current recommendations reduced mortality by 22% in older adults. A further increase in physical activity dose improved these benefits in a linear fashion. Older adults should be encouraged to include even low doses of MVPA in their daily lives.

KEYWORDS:

Elderly people; Health promotion; Meta-analysis; Physical activity; Public health

Comment in

PMID:
26238869
DOI:
10.1136/bjsports-2014-094306
[Indexed for MEDLINE]

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