Format

Send to

Choose Destination
Transcription. 2015;6(3):56-60. doi: 10.1080/21541264.2015.1059922.

Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations.

Author information

1
a Division of Structural and Synthetic Biology ; RIKEN Center for Life Science Technologies ; Suehiro-cho, Tsurumi-ku , Yokohama , Japan.

Abstract

RNA polymerase (RNAP) performs various tasks during transcription by changing its conformational states, which are gradually becoming clarified. A recent study focusing on the conformational transition of RNAP between the ratcheted and tight forms illuminated the structural principles underlying its functional operations.

KEYWORDS:

RNA polymerase; structure-function relationship; transcription; transcription factor; transcription regulation

PMID:
26226152
PMCID:
PMC4581356
DOI:
10.1080/21541264.2015.1059922
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center