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Behav Res Ther. 2015 Oct;73:8-18. doi: 10.1016/j.brat.2015.07.005. Epub 2015 Jul 21.

Cognitive behavior therapy for comorbid migraine and/or tension-type headache and major depressive disorder: An exploratory randomized controlled trial.

Author information

1
School of Applied Psychology and Menzies Health Institute Queensland, Griffith University, Mt Gravatt Campus, 176 Messines Ridge Road, Mt Gravatt, Queensland 4122, Australia. Electronic address: paul.martin@griffith.edu.au.
2
School of Psychology and Psychiatry, Monash University, Monash Medical Centre, 246 Clayton Road, Victoria 3168, Australia.
3
Melbourne School of Psychological Sciences, University of Melbourne, and Heidelberg Repatriation Hospital, 300 Waterdale Road, Heidelberg Heights, Victoria, 3081, Australia.
4
School of Health Sciences, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia; Australian College of Applied Psychology, Australia.

Abstract

Numerous studies have demonstrated comorbidity between migraine and tension-type headache on the one hand, and depression on the other. Presence of depression is a negative prognostic indicator for behavioral treatment of headaches. Despite the recognised comorbidity, there is a limited research literature evaluating interventions designed for comorbid headaches and depression. Sixty six participants (49 female, 17 male) suffering from migraine and/or tension-type headache and major depressive disorder were randomly allocated to a Routine Primary Care control group or a Cognitive Behavior Therapy group that also received routine primary care. The treatment program involved 12 weekly 50-min sessions administered by clinical psychologists. Participants in the treatment group improved significantly more than participants in the control group from pre-to post-treatment on measures of headaches, depression, anxiety, and quality of life. Improvements achieved with treatment were maintained at four month follow-up. Comorbid anxiety disorders were not a predictor of response to treatment, and the only significant predictor was gender (men improved more than women). The new integrated treatment program appears promising and worthy of further investigation.

KEYWORDS:

Cognitive behavior therapy; Depression; Migraine; Tension-type headache

PMID:
26226090
DOI:
10.1016/j.brat.2015.07.005
[Indexed for MEDLINE]

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