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J Pediatr Ophthalmol Strabismus. 2015 May-Jun;52(3):147-51.

Developmental Changes of Normal Pupil Size and Reactivity in Children.

Abstract

PURPOSE:

The goal of this study was to establish normative values for measurements of quantitative pupillometry in children.

METHODS:

Quantitative pupillometry measurements were obtained from children between 1 and 18 years of age being seen for either a well child check or other outpatient appointment.

RESULTS:

Maximum and minimum pupil size increased slightly with age; however, the correlation was weak (r = 0.29 and 0.19, respectively). Similarly weak correlations with age also were observed for maximum constriction velocity (r = -0.29) and dilation velocity (r = 0.27). Maximum (5.56 vs. 4.97 mm) and minimum (3.74 vs. 3.40 mm) pupil sizes were significantly larger in whites than in African Americans.

CONCLUSIONS:

Pupil size and reactivity show little correlation with age and are therefore suitable for further exploration in using pupillometry as a biomarker across the pediatric age range. Differences in race should be taken into consideration when pupillometry is used in mixed populations.

PMID:
26225382
[Indexed for MEDLINE]

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