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Trop Med Int Health. 2015 Nov;20(11):1549-1558. doi: 10.1111/tmi.12579. Epub 2015 Aug 18.

Association between maternal dental periapical infections and pregnancy outcomes: results from a cross-sectional study in Malawi.

Author information

1
Department for International Health, University of Tampere School of Medicine, Tampere, Finland.
2
Department of Radiology, Medical Imaging Center, Tampere University Hospital, Tampere, Finland.
3
Department of Nutrition, University of California, Davis, Davis, CA, USA.
4
Centre for Quantitative Medicine, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore.
5
FHI360, Food and Nutrition Technical Assistance III Project (FANTA), Washington, DC, USA.
6
School of Public Health, University of Malawi College of Medicine, Blantyre, Malawi.
7
Institute of Child Health, University College London, London, UK.
8
Department of Paediatrics, Tampere University Hospital, Tampere, Finland.

Abstract

OBJECTIVES:

Maternal infections are associated with intrauterine growth restriction (IUGR) and preterm birth (PTB). Dental infections are common in low-income settings, but their contribution to adverse pregnancy outcomes is unknown. We studied the epidemiology of dental periapical infections among pregnant women and their association to foetal growth restriction and the duration of pregnancy in a rural sub-Saharan African population.

METHODS:

This was a cross-sectional study on the association between maternal dental periapical infections and birth outcomes, in Malawi, Africa. We assessed oral health clinically and radiologically among recently delivered women with known duration of pregnancy and measured birthweight (BW), length and head circumference of their infants.

RESULTS:

Of 1024 analysed participants, 23.5% had periapical infections. Mean duration of pregnancy was 39.4 weeks, BW 2979 g and length 49.7 cm. Women with periapical infection had mean (95% CI) pregnancy duration 0.4 weeks (0.1-0.8) shorter and delivered infants with 79 g (13-145) lower BW and 0.5 cm (0.2-0.9) shorter neonatal length than women without periapical infection. The incidence of PTB was 10.0% among women with periapical infection and 7.3% among those without (adjusted difference 3.5%, 95% CI -1.1-8.1%). Corresponding prevalences for stunting were 20.9% and 14.2% (adjusted difference 9.0%, 95% CI 2.7%-15.2%). The population-attributable risk fraction attributable to periapical infection was 9.7% for PTB and 12.8% for stunting.

CONCLUSIONS:

Periapical infection was associated with shorter pregnancy duration and IUGR in the study area; interventions addressing this risk factor may improve birth outcomes in low-income settings.

KEYWORDS:

caries dentaires; caries dental; crecimiento intrauterino retardado; dental caries; duración del embarazo; duration of pregnancy; durée de la grossesse; femmes enceintes; infección periapical; infections; intrauterine growth restriction; mujer embarazada; parodontite; periapical infection; periodontitis; pregnant women; restriction de croissance intra-utérine

PMID:
26224026
DOI:
10.1111/tmi.12579
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