Format

Send to

Choose Destination
See comment in PubMed Commons below
Drugs Context. 2015 Jul 15;4:212282. doi: 10.7573/dic.212282. eCollection 2015.

A review of current treatment strategies for gestational diabetes mellitus.

Author information

1
Department of Pharmacy Practice, Auburn University Harrison School of Pharmacy, Auburn, AL, USA.

Abstract

Approximately 90% of diabetes cases in pregnant women are considered gestational diabetes mellitus (GDM). It is well known that uncontrolled glucose results in poor pregnancy outcomes in both the mother and fetus. Worldwide there are many guidelines with recommendations for appropriate management strategies for GDM once lifestyle modifications have been instituted and failed to achieve control. The efficacy and particularly the safety of other treatment modalities for GDM has been the source of much debate in recent years. Studies that have demonstrated the safety and efficacy of both glyburide and metformin in the management of patients with GDM will be reviewed. There is a lack of evidence with other oral and injectable non-insulin agents to control blood glucose in GDM. The role of insulin will be discussed, with emphasis on insulin analogs. Ideal patient characteristics for each treatment modality will be reviewed. In addition, recommendations for postpartum screening of patients will be described as well as recommendations for use of agents to manage subsequent type 2 diabetes in patients who are breastfeeding.

KEYWORDS:

fetal macrosomia; gestational diabetes; glyburide; hypoglycemia; hypoglycemic agents; insulin; long-acting insulin; metformin; postnatal care; short-acting insulin

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Just Medical Media Limited Icon for PubMed Central
    Loading ...
    Support Center