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J Microbiol Immunol Infect. 2016 Aug;49(4):595-9. doi: 10.1016/j.jmii.2015.05.010. Epub 2015 Jun 27.

Investigation of mechanisms and molecular epidemiology of linezolid nonsusceptible Enterococcus faecalis isolated from a teaching hospital in China.

Author information

1
Department of Clinical Laboratory, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
2
School of Laboratory Medicine and life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
3
Department of Clinical Laboratory, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. Electronic address: wyztli@163.com.

Abstract

The epidemiological and molecular characteristics of eight linezolid nonsusceptible Enterococcus faecalis isolated from a teaching hospital in China (January to July 2014) were investigated. The target site modifications and cfr gene associated with linezolid resistance were not found. Results of the epidemiological investigation indicated that linezolid resistance possibly occurred on several independent occasions and was often not related to linezolid administration.

KEYWORDS:

23S rRNA; Enterococcus faecalis; Linezolid nonsusceptible; Multilocus sequence typing; Pulsed-field gel electrophoresis

PMID:
26210761
DOI:
10.1016/j.jmii.2015.05.010
[Indexed for MEDLINE]
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