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Hist Philos Life Sci. 2015 Dec;37(4):413-29. doi: 10.1007/s40656-015-0081-y. Epub 2015 Jul 24.

Is synthetic biology mechanical biology?

Author information

1
Philosophy Section, Department of Media, Cognition, and Communication, University of Copenhagen, Copenhagen, Denmark. suneh@hum.ku.dk.

Abstract

A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines. In the paper I investigate the ontological and heuristic significance of the machine analogy in synthetic biology. I argue that the use of the machine analogy and the aim of producing rationally designed organisms does not necessarily imply a commitment to mechanical biology. The ideal of applying engineering principles to biology is best understood as expressing recognition of the machine-unlikeness of natural organisms and the limits of human cognition. The paper suggests an interpretation of the identification of organisms with machines in synthetic biology according to which it expresses a strategy for representing, understanding, and constructing living systems that are more machine-like than natural organisms.

PMID:
26205204
DOI:
10.1007/s40656-015-0081-y
[Indexed for MEDLINE]

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