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Int J Biomed Sci. 2015 Jun;11(2):54-60.

Evaluation of the Effect of Mega MSM on Improving Joint Function in Populations Experiencing Joint Degeneration.

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School of Public Health, Shanghai Jiao Tong University, China;
Beijing University of Chinese Medicine;
Tangqiao Community Health Service Center, Pudong New District, China;
Department of Research, DRM Resources, 1683 Sunflower Avenue, Costa Mesa, CA 92626, USA;
Department of Pathology and Laboratory Medicine, in UCLA Medical Center, University of California, Los Angeles, CA, USA.


Joint degeneration has become a commonplace problem in aging populations. The main clinical manifestations include joint pain, joint stiffness and joint swelling with functional disorder. Mega MSM is a nutritional supplement that may provide potential relief for joint problems associated with joint degeneration. The current experiment performed was a 12-week, randomized, double-blind, controlled study conducted on populations in China experiencing joint degeneration. The objective of the study was to determine whether the daily use of Mega MSM capsules could improve joint function, relieve symptoms of joint degeneration and improve the quality of life in aging populations. A total of 100 male and female participants over 50 years old who had at least one of the related symptoms of joint degeneration (joint pain, joint stiffness, joint swelling, difficulty walking, difficulty getting up from bed and difficulty going down stairs) were recruited and their symptoms of joint degeneration before and after the intervention were recorded. In this study, Mega MSM shows positive effects in improving joint function, relieving symptoms associated with joint degeneration and improving the quality of life in aging populations.


Joint degeneration; Mega MSM; joint pain; joint stiffness; joint swelling; quality of life


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