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Antimicrob Agents Chemother. 2015 Aug;59(8):4375-8. doi: 10.1128/AAC.00553-15.

Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae.

Author information

1
MetroHealth Medical Center, Cleveland, Ohio, USA University Hospitals Case Medical Center, Cleveland, Ohio, USA.
2
MetroHealth Medical Center, Cleveland, Ohio, USA.
3
MetroHealth Medical Center, Cleveland, Ohio, USA Case Western Reserve University, Cleveland, Ohio, USA.
4
Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
5
Case Western Reserve University, Cleveland, Ohio, USA Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
6
Case Western Reserve University, Cleveland, Ohio, USA University Hospitals Case Medical Center, Cleveland, Ohio, USA.
7
University of North Carolina, Chapel Hill, North Carolina, USA.
8
Case Western Reserve University, Cleveland, Ohio, USA Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA federico.perez@va.gov robert.bonomo@va.gov d.paterson1@uq.edu.au.
9
University of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, Brisbane, Australia federico.perez@va.gov robert.bonomo@va.gov d.paterson1@uq.edu.au.
10
University of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, Brisbane, Australia.

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant. This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.

PMID:
26185273
PMCID:
PMC4505232
DOI:
10.1128/AAC.00553-15
[Indexed for MEDLINE]
Free PMC Article

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