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J Clin Ultrasound. 2016 Jan;44(1):34-9. doi: 10.1002/jcu.22273. Epub 2015 Jul 14.

The effect of maternal obesity on sonographic fetal weight estimation and perinatal outcome in pregnancies complicated by fetal growth restriction.

Author information

1
Rotunda Hospital, Dublin, Ireland.
2
Royal College of Surgeons in Ireland, Dublin, Ireland.
3
Coombe Women and Infants University Hospital, Dublin, Ireland.
4
UCD Center for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
5
UCD Obstetrics and Gynecology, School of Medicine and Medical Science, National Maternity Hospital, Dublin, Ireland.
6
University College Cork, Cork University Maternity Hospital, Cork, Ireland.
7
Royal Jubilee Maternity Hospital, Belfast, Ireland.
8
National University of Ireland, Galway, Ireland.
9
Graduate Entry Medical School, University of Limerick, Limerick, Ireland.

Abstract

PURPOSE:

Maternal obesity represents a challenge in the sonographic (US) assessment of fetal weight, and is a recognized risk factor for adverse pregnancy outcome. The objective of this secondary analysis of data from the Prospective Observational Trial to Optimize Pediatric Health in fetal growth restriction (FGR) Study (PORTO) was to describe the effect of maternal obesity on the accuracy of US in determining the estimated fetal weight (EFW) and the perinatal outcome of pregnancies affected by FGR.

METHODS:

Between 2010 and 2012, 1,116 women with nonanomalous singleton pregnancies with an EFW in less than the tenth centile were recruited for the PORTO study. Maternal body mass index (BMI) was divided into five subcategories: normal (BMI < 24.9 kg/m(2) ), overweight (25-29.9), obese class 1 (30-34.9), obese class 2 (35-39.9), and obese class 3 (>40). The accuracy of the EFW was determined in women who delivered within 2 weeks of their last US scan. Perinatal outcomes were analyzed by BMI subcategory.

RESULTS:

Of the 1,074 patients with complete records, 691 (64%) were of normal weight, 258 (24%) were overweight, 93 (9%) were in obese class 1, 32 (3%) were in obese class 2, and none were in obese class 3. Overall, the EFW determined prior to delivery was within 6% of the actual birth weight in all BMI subcategories. Overweight and obese women delivered more commonly by cesarean section and at earlier gestational ages than did women with a normal BMI (p = 0.0008), resulting in lower birth weights (p = 0.0031) and significantly increased composite perinatal morbidity (p < 0.0001) and mortality (p = 0.0215) rates.

CONCLUSIONS:

US examination is reliable for assessing the weight of fetuses with FGR in overweight women. Maternal obesity, however, has a significant adverse effect on perinatal outcomes. Thus, health education should focus on awareness of this adverse effect, with optimization of prepregnancy weight as its main goal.

KEYWORDS:

fetal growth restriction; fetal weight estimation; maternal obesity; perinatal outcome; ultrasonography

PMID:
26179577
DOI:
10.1002/jcu.22273
[Indexed for MEDLINE]

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