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Expert Rev Clin Immunol. 2015;11(10):1121-30. doi: 10.1586/1744666X.2015.1067606. Epub 2015 Jul 15.

The role of exercise in the management of rheumatoid arthritis.

Author information

1
c 3 Department of Physical Education and Sports Science, University of Thessaly, Thessaly, Greece.
2
b 2 Department of Rheumatology, Dudley Group NHS Foundation Trust, Russell's Hall Hospital, Dudley, West Midlands, UK.
3
d 4 School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
4
e 5 Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK.

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with significant functional impairment and increased risk for cardiovascular disease. Along with pharmacological therapy, exercise seems to be a very promising intervention to improve disease-related outcomes, including functional ability and systemic manifestations, such as the increased cardiovascular risk. In this review, we discuss the physiological mechanisms by which exercise improves inflammation, cardiovascular risk and psychological health in patients with rheumatoid arthritis (RA) and describe in detail how exercise can be incorporated in the management of this disease using real examples from our clinical practice.

KEYWORDS:

arthritis; cardiovascular disease; exercise; exercise as medicine; inflammation; physical activity; rheumatoid arthritis

PMID:
26178249
DOI:
10.1586/1744666X.2015.1067606
[Indexed for MEDLINE]

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