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PLoS One. 2015 Jul 15;10(7):e0132614. doi: 10.1371/journal.pone.0132614. eCollection 2015.

Visualizing Risk Prediction Models.

Author information

1
KU Leuven, Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Leuven, Belgium; iMinds Medical IT, KU Leuven, Leuven, Belgium.
2
KU Leuven, Department of Development and Regeneration, Leuven, Belgium.

Abstract

OBJECTIVE:

Risk prediction models can assist clinicians in making decisions. To boost the uptake of these models in clinical practice, it is important that end-users understand how the model works and can efficiently communicate its results. We introduce novel methods for interpretable model visualization.

METHODS:

The proposed visualization techniques are applied to two prediction models from the Framingham Heart Study for the prediction of intermittent claudication and stroke after atrial fibrillation. We represent models using color bars, and visualize the risk estimation process for a specific patient using patient-specific contribution charts.

RESULTS:

The color-based model representations provide users with an attractive tool to instantly gauge the relative importance of the predictors. The patient-specific representations allow users to understand the relative contribution of each predictor to the patient's estimated risk, potentially providing insightful information on which to base further patient management. Extensions towards non-linear models and interactions are illustrated on an artificial dataset.

CONCLUSION:

The proposed methods summarize risk prediction models and risk predictions for specific patients in an alternative way. These representations may facilitate communication between clinicians and patients.

PMID:
26176945
PMCID:
PMC4503430
DOI:
10.1371/journal.pone.0132614
[Indexed for MEDLINE]
Free PMC Article

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