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Urology. 2015 Sep;86(3):432-8. doi: 10.1016/j.urology.2015.07.001. Epub 2015 Jul 10.

Targeted Prostate Biopsy: Lessons Learned Midst the Evolution of a Disruptive Technology.

Author information

1
Department of Urology, University of California at Los Angeles, Los Angeles, CA.
2
Department of Urology, University of California at Los Angeles, Los Angeles, CA; Departments of Urology and Biomedical Engineering, University of California at Los Angeles, Los Angeles, CA.
3
Department of Radiology, University of California at Los Angeles, Los Angeles, CA.
4
Department of Urology, University of California at Los Angeles, Los Angeles, CA. Electronic address: Lmarks@mednet.ucla.edu.

Abstract

Lessons learned during a 6-year experience with more than 1200 patients undergoing targeted prostate biopsy via MRI/ultrasound fusion are reported: (1) the procedure is safe and efficient, requiring some 15-20 minutes in an office setting; (2) MRI is best performed by a radiologist with specialized training, using a transabdominal multiparametric approach and preferably a 3T magnet; (3) grade of MRI suspicion is the most powerful predictor of biopsy results, eg, Grade 5 usually represents cancer; (4) some potentially important cancers (15%-30%) are MRI-invisible; (5) Targeted biopsies provide >80% concordance with whole-organ pathology. Early enthusiasm notwithstanding, cost-effectiveness is yet to be resolved, and the technologies remain in evolution.

PMID:
26166671
PMCID:
PMC4569505
DOI:
10.1016/j.urology.2015.07.001
[Indexed for MEDLINE]
Free PMC Article

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