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Expert Rev Anticancer Ther. 2015;15(8):931-41. doi: 10.1586/14737140.2015.1054814. Epub 2015 Jul 11.

Optimal management of resectable gastric adenocarcinoma.

Author information

1
Department of Radiation Oncology at Dana Farber Cancer Institute/Brigham and Women's Hospital, Harvard Radiation Oncology Program, 75 Francis Street, Boston, MA 02215, USA.

Abstract

The worldwide incidence of gastric adenocarcinoma has rapidly declined in the past century, but gastric cancer remains the fifth most common malignancy in the world. Approximately half of all cases of gastric cancer are diagnosed in Eastern Asia. In this review, we provide an overview of the landmark studies investigating neoadjuvant and adjuvant therapies in resectable gastric cancer and highlight ongoing efforts to define optimal population-adapted management strategies.

KEYWORDS:

chemoradiation; chemotherapy; gastric adenocarcinoma; locally advanced; multimodality therapy; radiation therapy; respectable; stomach cancer

PMID:
26165449
DOI:
10.1586/14737140.2015.1054814
[Indexed for MEDLINE]

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