Format

Send to

Choose Destination
Qual Life Res. 2016 Jan;25(1):45-9. doi: 10.1007/s11136-015-1065-9. Epub 2015 Jul 11.

How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?

Author information

1
Division of Psychiatry, University College London, Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ, England, UK. e.aguirre@ucl.ac.uk.
2
Division of Psychiatry, University College London, Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ, England, UK. s.kang@bangor.ac.uk.
3
Division of Psychiatry, University College London, Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ, England, UK. z.hoare@bangor.ac.uk.
4
Division of Psychiatry, University College London, Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ, England, UK. r.t.edwards@bangor.ac.uk.
5
Division of Psychiatry, University College London, Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ, England, UK. m.orrell@ucl.ac.uk.

Abstract

PURPOSE:

This study aimed to assess and compare the psychometric performance of the EQ-5D in relation to other dementia-specific measures, the QoL-AD and DEMQoL, within a psychosocial intervention study.

METHODS:

Two hundred and seventy-two people with dementia completed the EQ-5D, DEMQoL and QoL-AD. Convergent and discriminant validity of the measures were assessed, and inter-rater reliability was tested by comparing the self-reported and proxy scores of the measures. Internal consistency was tested using Cronbach's alpha.

RESULTS:

Results satisfy convergent validity amongst the three outcome measures. EQ-5D, DEMQoL and QoL-AD total scores were shown to be significantly correlated with each other (p < 0.001) in both participants with dementia and proxy reports. Results also satisfied discriminant validity for participant EQ-5D, DEMQoL and QoL-AD total scores. In relation to reliability between self and proxy scores, the EQ-5D showed higher reliability scores between participant and proxy total scores for mild and moderate level of cognitive impairment and performed better than the dementia-specific measures. Reliability assessed through Cronbach's alpha was satisfactory, indicating adequate internal consistency of all three measures.

CONCLUSIONS:

The results suggest that the EQ-5D might have advantages over other dementia-specific measures, and it could be used routinely and as a stand-alone measure of quality of life in dementia research.

KEYWORDS:

DEMQoL; Dementia; EQ-5D; QoL-AD; Quality of life; Utility

PMID:
26163146
DOI:
10.1007/s11136-015-1065-9
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center