Format

Send to

Choose Destination
Sci Rep. 2015 Jul 9;5:12002. doi: 10.1038/srep12002.

Plasmakinetic resection technology for the treatment of benign prostatic hyperplasia: evidence from a systematic review and meta-analysis.

Author information

1
1] Department of Urology, Zhongnan Hospital, Wuhan University, Wuhan, People's Republic of China [2] Center for Evidence-based and Translational Medicine, Wuhan University, Wuhan, People's Republic of China.
2
Chinese Evidence-Based Center and Chinese Cochrane Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
3
Department of Hematology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
4
Department of Urology, Zhongnan Hospital, Wuhan University, Wuhan, People's Republic of China.
5
Center for Evidence-based and Translational Medicine, Wuhan University, Wuhan, People's Republic of China.
6
Department of Epidemiology, School of Public Health, Wuhan University, Wuhan, People's Republic of China.

Abstract

The aim of this study was to compare plasmakinetic resection of the prostate (PKRP) with transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH) in terms of efficacy and safety. Published RCTs were searched from PubMed, Embase, Science Citation Index, and Cochrane Library up to April 10, 2014. After methodological quality assessment and data extraction, meta-analysis was performed using the STATA 12.0 software. 18 reports of 16 RCTs were included in this analysis. Meta-analyses showed that PKRP significantly improved Qmax at 12 months, but no significant difference was found for other efficacy outcomes. In terms of safety, treatment of PKRP was associated with reduced drop in serum sodium, lower TUR syndrome, reduced need of blood transfusion, clot retention, and shorter catheterization time and hospital stay; in contrast, there were no significant differences in the analysis of operative time, postoperative fever, and long-term postoperative complications. In summary, current evidence suggests that, although PKRP and TURP are both effective for BPH, PKRP is associated with additional potential benefits in efficacy and more favorable safety profile. It may be possible that PKRP may replace the TURP in the future and become a new standard surgical procedure.

PMID:
26156138
PMCID:
PMC4496666
DOI:
10.1038/srep12002
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center