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Br J Haematol. 2016 Mar;172(5):815-9. doi: 10.1111/bjh.13542. Epub 2015 Jul 6.

The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.

Author information

1
Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.
2
Salzburg Cancer Research Institute, Salzburg, Austria.
3
Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria. t.hartmann@salk.at.
4
Salzburg Cancer Research Institute, Salzburg, Austria. t.hartmann@salk.at.

KEYWORDS:

AKT; chemoresistance; chronic lymphocytic leukaemia; microenvironment; survival

PMID:
26147087
PMCID:
PMC4832298
DOI:
10.1111/bjh.13542
[Indexed for MEDLINE]
Free PMC Article

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