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Clin Immunol. 2015 Dec;161(2):391-3. doi: 10.1016/j.clim.2015.06.011. Epub 2015 Jun 27.

Effects of enzyme replacement therapy on immune function in ADA deficiency patient.

Author information

1
Department of Human Genetics, National Research Institute for Child Health and Development, Japan.
2
Department of General Pediatrics &Interdisciplinary Medicine, National Center for Child Health and Development, Japan.
3
Clinical Laboratory Medicine, National Center for Child Health and Development, Japan.
4
Center for Stem Cell Biology and Regenerative Medicine, Tokyo University, Japan.
5
Department of Pediatrics, Hokkaido University, Japan.
6
Department of Biochemistry, Duke University Medical Center, USA.
7
Department of Human Genetics, National Research Institute for Child Health and Development, Japan. Electronic address: onodera-m@ncchd.go.jp.

KEYWORDS:

Adenosine deaminase deficiency; Enzyme replacement therapy; Immune reconstitution; PEG-ADA; Severe combined immunodeficiency; Stem cell gene therapy

PMID:
26122173
DOI:
10.1016/j.clim.2015.06.011
[Indexed for MEDLINE]

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