Format

Send to

Choose Destination
Neuroimage. 2015 Dec;123:245-52. doi: 10.1016/j.neuroimage.2015.06.054. Epub 2015 Jun 26.

Lateralized modulation of posterior alpha oscillations in children.

Author information

1
Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Kapittelweg 29, 6525 EN Nijmegen, Netherlands; Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6526 GC Nijmegen, Netherlands. Electronic address: m.vollebregt@donders.ru.nl.
2
Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Kapittelweg 29, 6525 EN Nijmegen, Netherlands. Electronic address: johanna.zumer@gmail.com.
3
Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Kapittelweg 29, 6525 EN Nijmegen, Netherlands; Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6526 GC Nijmegen, Netherlands. Electronic address: n.terhuurne@karakter.com.
4
Center for Neuroscience, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, 1090 GB Amsterdam, The Netherlands. Electronic address: jesminne@gmail.com.
5
Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Kapittelweg 29, 6525 EN Nijmegen, Netherlands; Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6526 GC Nijmegen, Netherlands. Electronic address: jan.buitelaar@radboudumc.nl.
6
Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Kapittelweg 29, 6525 EN Nijmegen, Netherlands. Electronic address: o.jensen@donders.ru.nl.

Abstract

The evidence for a functionally inhibitory role of alpha oscillations is growing stronger, mostly derived from studies in healthy adults investigating spatial attention. It remains unexplored if the modulation of alpha band oscillations plays a similar functional role in typically developing children. The aim of this study was to characterize alpha modulations in children in relation to attentional performance. To this end, the posterior alpha activity (8-12Hz) in children between 7 and 10years old was measured using EEG while they performed a visuospatial covert attention task. We found that the alpha activity decreased in the hemisphere contralateral to the attended hemifield, whereas it relatively increased in the other hemisphere. In addition, we found that the degree of lateralized alpha modulation predicted performance on the attention task by negatively predicting the response time on invalid trials. Of note, children who were behaviorally less influenced by spatial cueing also were children with a clear lateralized alpha modulation pattern, with a significantly stronger alpha lateralization in the left hemisphere than children who were influenced more by spatial cueing. In addition, a bias to the right visual field such as that commonly observed in children, was significantly smaller or absent in the children influenced least by spatial cueing. Among all children, the magnitude of this visual field bias was positively related to the ability to modulate alpha activity. In conclusion, we have shown that the pattern of alpha oscillations modulated by attention is already present in 7-10year old typically developing children. Although a similar pattern is observed in adults, the consequences for behavior are different. The fact that alpha modulation is already present at this age opens up the possibility of using hemispheric alpha lateralization as a tool to study the physiological basis of attention deficits in clinical disorders such as ADHD.

KEYWORDS:

Alpha modulation; Attentional bias; Children; Covert attention; Development; Electroencephalography

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center