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Ideggyogy Sz. 2014 Mar 30;67(3-4):91-4.

HANS SELYE 70 YEARS LATER: STEROIDS, STRESS ULCERS & H. PYLORI.

Abstract

Although Hans Selye is mostly known for his discovery & development of the stress concept, he also introduced the first physiologically sound, structure-activity classification of steroids that was also based on the chemical structure of steroids in 1943. He not only introduced the names of glucocorticoids & mineralocorticoids but discovered the anti- & pro-inflammatory properties, respectively, of these steroids in animal models. Furthermore, he not only described the first stress-induced gastric ulcers in rats (1936) & characterized the first human 'stress ulcers' during the air-raids in London during World War 11 (1943). Thus, Selye was a much more productive & creative scientist than it is generally considered.

PMID:
26118247
[Indexed for MEDLINE]

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