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Magn Reson Imaging. 2015 Oct;33(8):951-5. doi: 10.1016/j.mri.2015.06.002. Epub 2015 Jun 25.

Unenhanced breast MRI (STIR, T2-weighted TSE, DWIBS): An accurate and alternative strategy for detecting and differentiating breast lesions.

Author information

1
DIM - Interdisciplinary Department of Medicine - Section of Diagnostic Imaging - Aldo Moro University of Bari Medical School, Piazza Giulio Cesare 11, 70124 Bari, Italy.
2
DIM - Interdisciplinary Department of Medicine - Section of Diagnostic Imaging - Aldo Moro University of Bari Medical School, Piazza Giulio Cesare 11, 70124 Bari, Italy. Electronic address: marco.moschetta@gmail.com.

Abstract

PURPOSE:

To assess the role of STIR, T2-weighted TSE and DWIBS sequences for detecting and characterizing breast lesions and to compare unenhanced (UE)-MRI results with contrast-enhanced (CE)-MRI and histological findings, having the latter as the reference standard.

MATERIALS AND METHODS:

Two hundred eighty consecutive patients (age range, 27-73 years; mean age±standard deviation (SD), 48.8±9.8years) underwent MR examination with a diagnostic protocol including STIR, T2-weighted TSE, THRIVE and DWIBS sequences. Two radiologists blinded to both dynamic sequences and histological findings evaluated in consensus STIR, T2-weighted TSE and DWIBS sequences and after two weeks CE-MRI images searching for breast lesions. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy for UE-MRI and CE-MRI were calculated. UE-MRI results were also compared with CE- MRI.

RESULTS:

UE-MRI sequences obtained sensitivity, specificity, diagnostic accuracy, PPV and NPV values of 94%, 79%, 86%, 79% and 94%, respectively. CE-MRI sequences obtained sensitivity, specificity, diagnostic accuracy, PPV and NPV values of 98%, 83%, 90%, 84% and 98%, respectively. No statistically significant difference between UE-MRI and CE-MRI was found.

CONCLUSION:

Breast UE-MRI could represent an accurate diagnostic tool and a valid alternative to CE-MRI for evaluating breast lesions. STIR and DWIBS sequences allow to detect breast lesions while T2-weighted TSE sequences and ADC values could be useful for lesion characterization.

KEYWORDS:

Breast; DWIBS; MRI; STIR; T2 TSE; Unenhanced imaging

PMID:
26117691
DOI:
10.1016/j.mri.2015.06.002
[Indexed for MEDLINE]

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