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Rheumatology (Oxford). 2015 Nov;54(11):2015-24. doi: 10.1093/rheumatology/kev201. Epub 2015 Jun 26.

Consensus best practice pathway of the UK Scleroderma Study Group: digital vasculopathy in systemic sclerosis.

Author information

1
Centre for Musculoskeletal Research, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, michael.hughes-6@postgrad.manchester.ac.uk.
2
Centre for Rheumatology, Royal Free Hospital, London.
3
Institute of Ageing and Chronic Disease, Faculty of Health & Life Sciences, University of Liverpool.
4
Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
5
Department for Dermatology and Venereology, University of Cologne, Cologne, Germany.
6
Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne and.
7
Department of Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, UK.
8
Centre for Musculoskeletal Research, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester.

Abstract

OBJECTIVE:

Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres.

METHODS:

The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy.

RESULTS:

This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice.

CONCLUSION:

A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.

KEYWORDS:

Raynaud’s phenomenon; critical digital ischaemia; digital ulcer; digital vasculopathy; scleroderma; systemic sclerosis

PMID:
26116156
DOI:
10.1093/rheumatology/kev201
[Indexed for MEDLINE]

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