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Eur Heart J. 2015 Oct 1;36(37):2491-9. doi: 10.1093/eurheartj/ehv288. Epub 2015 Jun 25.

Pregnancy in women with congenital heart disease.

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Adult Congenital Heart Disease Program, Department of Cardiology, University Heart Center, Raemistrasse 100, 8091 Zurich, Switzerland
Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.


Congenital heart defects are the most common birth defects. Major advances in open-heart surgery have led to rapidly evolving cohorts of adult survivors and the majority of affected women now survive to childbearing age. The risk of cardiovascular complications during pregnancy and peripartum depends on the type of the underlying defect, the extent and severity of residual haemodynamic lesions and comorbidities. Careful individualized, multi-disciplinary pre-pregnancy risk assessment and counselling, including assessment of risks in the offspring and estimation on long-term outcomes of the underlying heart defect, will enable informed decision making. Depending on the estimated risks, a careful follow-up plan during pregnancy as well as a detailed plan for delivery and postpartum care can reduce the risks and should be made by the multi-disciplinary team.


Congenital heart disease; Delivery; Labour; Pregnancy

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