Format

Send to

Choose Destination
Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1341-9. doi: 10.1158/1055-9965.EPI-14-1396. Epub 2015 Jun 23.

Cluster-Randomized Trial to Increase Hepatitis B Testing among Koreans in Los Angeles.

Author information

1
Fielding School of Public Health, Jonsson Comprehensive Cancer Center, UCLA Kaiser Permanente Center for Health Equity, University of California, Los Angeles, California. bastani@ucla.edu.
2
Fielding School of Public Health, Jonsson Comprehensive Cancer Center, UCLA Kaiser Permanente Center for Health Equity, University of California, Los Angeles, California.
3
Family and Community Medicine, University of New Mexico, Albuquerque, New Mexico.
4
Division of Biostatistics, Department of Public Health Sciences, University of California Davis, Davis, California.
5
Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
6
Division of Hematology and Oncology, Department of Internal Medicine, University of California Davis, Davis, California.
7
Fred Hutchinson Cancer Research Center, Seattle, Washington.

Abstract

BACKGROUND:

In the United States, Korean immigrants experience a disproportionately high burden of chronic hepatitis B (HBV) viral infection and associated liver cancer compared with the general population. However, despite clear clinical guidelines, HBV serologic testing among Koreans remains persistently suboptimal.

METHODS:

We conducted a cluster-randomized trial to evaluate a church-based small group intervention to improve HBV testing among Koreans in Los Angeles. Fifty-two Korean churches, stratified by size (small, medium, large) and location (Koreatown versus other), were randomized to intervention or control conditions. Intervention church participants attended a single-session small-group discussion on liver cancer and HBV testing, and control church participants attended a similar session on physical activity and nutrition. Outcome data consisted of self-reported HBV testing obtained via 6-month telephone follow-up interviews.

RESULTS:

We recruited 1,123 individuals, 18 to 64 years of age, across the 52 churches. Ninety-two percent of the sample attended the assigned intervention session and 86% completed the 6-month follow-up. Sample characteristics included were as follows: mean age 46 years, 65% female, 97% born in Korea, 69% completed some college, and 43% insured. In an intent-to-treat analysis, the intervention produced a statistically significant effect (OR = 4.9, P < 0.001), with 19% of intervention and 6% of control group participants reporting a HBV test.

CONCLUSION:

Our intervention was successful in achieving a large and robust effect in a population at high risk of HBV infection and sequelae.

IMPACT:

The intervention was fairly resource efficient and thus has high potential for replication in other high-risk Asian groups.

PMID:
26104909
PMCID:
PMC4560609
DOI:
10.1158/1055-9965.EPI-14-1396
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center