Format

Send to

Choose Destination
See comment in PubMed Commons below
Pediatrics. 2015 Jul;136(1):e215-24. doi: 10.1542/peds.2015-0673. Epub 2015 Jun 22.

Comparative Effectiveness Research Through a Collaborative Electronic Reporting Consortium.

Author information

1
The Pediatric Research Consortium, Department of Biomedical and Health Informatics, Center for Pediatric Clinical Effectiveness, and PolicyLab at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Pediatric Research in Office Settings, American Academy of Pediatrics, Elk Grove Village, Illinois; fiks@email.chop.edu.
2
Department of Biomedical and Health Informatics.
3
Pediatric Research in Office Settings, American Academy of Pediatrics, Elk Grove Village, Illinois;
4
Boston University School of Medicine, Boston, Massachusetts;
5
Departments of Internal Medicine, Pediatrics, and Epidemiology and Biostatistics and the Center for Clinical Informatics Research and Education, The MetroHealth System, Case Western Reserve University, Cleveland, Ohio;
6
American Academy of Family Physicians National Research Network, Leawood, Kansas; and.
7
Pediatric Research in Office Settings, American Academy of Pediatrics, Elk Grove Village, Illinois; Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont.

Abstract

The United States lacks a system to use routinely collected electronic health record (EHR) clinical data to conduct comparative effectiveness research (CER) on pediatric drug therapeutics and other child health topics. This Special Article describes the creation and details of a network of EHR networks devised to use clinical data in EHRs for conducting CER, led by the American Academy of Pediatrics Pediatric Research in Office Settings (PROS). To achieve this goal, PROS has linked data from its own EHR-based "ePROS" network with data from independent practices and health systems across the United States. Beginning with 4 of proof-of-concept retrospective CER studies on psychotropic and asthma medication use and side effects with a planned full-scale prospective CER study on treatment of pediatric hypertension, the Comparative Effectiveness Research Through Collaborative Electronic Reporting (CER(2)) collaborators are developing a platform to advance the methodology of pediatric pharmacoepidemiology. CER(2) will provide a resource for future CER studies in pediatric drug therapeutics and other child health topics. This article outlines the vision for and present composition of this network, governance, and challenges and opportunities for using the network to advance child health and health care. The goal of this network is to engage child health researchers from around the United States in participating in collaborative research using the CER(2) database.

PMID:
26101357
DOI:
10.1542/peds.2015-0673
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center