Perfluorinated chemicals in blood serum of inhabitants in central Poland in relation to gender and age

Sci Total Environ. 2015 Nov 1:532:548-55. doi: 10.1016/j.scitotenv.2015.06.050. Epub 2015 Jun 20.

Abstract

The goal of this paper is to determine concentrations of seven selected perfluoroalkylated substances (PFASs): perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorododecanoic acid (PFDoDA) in the blood serum of men and women of reproductive age from the central region of Poland. The relation between sex of tested subjects and the levels of compounds in blood serum of humans will also be considered and analysed as an element of the risk assessment. The study was made on the blood serum samples collected from 253 women and 176 men of reproductive age between 20 and 44 years from Warsaw and surrounding areas. Higher concentrations of five (PFOS, PFOA, PFNA, PFDA, PFUnDA) from among seven selected PFASs were observed in men in comparison to women from the same populations. Only the concentrations of PFHxS and PFDoDA were slightly higher in women than in men. These differences were statistically significant in all cases, except for PFUnDA. The hypothesis that the concentrations of said compounds increase with age of the test subjects, regardless of gender has not been confirmed.

Keywords: PFASs; PFOA; PFOS; POPs; Serum levels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alkanesulfonic Acids / blood
  • Caprylates / blood
  • Decanoic Acids / blood
  • Environmental Exposure / analysis*
  • Environmental Exposure / statistics & numerical data
  • Environmental Pollutants / blood*
  • Female
  • Fluorocarbons / blood*
  • Humans
  • Lauric Acids / blood
  • Male
  • Middle Aged
  • Poland
  • Serum
  • Young Adult

Substances

  • Alkanesulfonic Acids
  • Caprylates
  • Decanoic Acids
  • Environmental Pollutants
  • Fluorocarbons
  • Lauric Acids
  • perfluorodecanoic acid
  • perfluorooctanoic acid
  • perfluorooctane sulfonic acid
  • perflexane
  • perfluorododecanoic acid