Format

Send to

Choose Destination
Indian J Dent. 2015 Apr-Jun;6(2):60-4. doi: 10.4103/0975-962X.155876.

Microbiologic Evaluation of Matricaria and Chlorhexidine against E. faecalis and C. albicans.

Author information

1
Department of Conservative Dentistry and Endodontics, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India.
2
Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.

Abstract

OBJECTIVE:

To evaluate the antimicrobial activity of different concentrations of Matricaria chamomilla and Chlorhexidine gel against Candida albicans and Enterococcus faecalis.

MATERIALS AND METHODS:

The agar diffusion test was used to evaluate the antimicrobial activity of 15%, 25% Matricaria chamomilla in aq. base and 2% chlorhexidine gel against C. albicans (ATCC 24433) and E. faecalis (ATCC 24212) strains. Vancomycin was used as the positive control for E. faecalis and fluconazole for C. albicans . The agar plates were incubated at 37°C for 48 h after which the zone of inhibition were measured separately for each material. Data thus obtained were statistically analyzed using the Wilcoxon rank-order test.

RESULTS:

2% chlorhexidine showed maximum inhibitory zone for C. albicans (33.26 mm) and E. faecalis (24.54 mm). 25% Matricaria showed zones of 24.16 mm and 20.62 mm for C. albicans and E. faecalis, respectively. 15% Matricaria did not show any antimicrobial activity (0 mm).

CONCLUSION:

The results of the current in vitro study suggest that 25% Matricaria can be used as an antimicrobial agent, but it is less effective than 2% chlorhexidine gluconate gel against C. albicans and E. faecalis. Matricaria at a lesser concentration of 15% aq. base is ineffective against both the microorganisms.

KEYWORDS:

Agar diffusion test; Candida albicans; Enterococcus faecalis; Matricaria chamomilla; chlorhexidine

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center