Resolution of superimposed pre-eclampsia, and improvement in umbilical artery flow in a surviving twin after intrauterine demise of its co-twin

J Obstet Gynaecol Res. 2015 Sep;41(9):1473-7. doi: 10.1111/jog.12725. Epub 2015 Jun 21.

Abstract

Pre-eclampsia has a progressive clinical course, and is only cured by delivery of the placenta. We report a 30-year-old G1P0 with dichorionic twins, discordant growth and chronic hypertension who developed superimposed pre-eclampsia in her 21st week of gestation. After intrauterine demise of the severely growth-restricted twin, the superimposed pre-eclampsia resolved. The surviving twin initially had absent end diastolic flow, which resolved after the demise. A healthy 1935-g neonate with Apgar 9/9 was delivered at 34 weeks. Antenatal resolution of pre-eclampsia is extremely rare and resolution of superimposed pre-eclampsia has not, to our knowledge, been reported.

Keywords: dichorionic twins; intrauterine fetal demise; superimposed pre-eclampsia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fetal Death*
  • Fetal Growth Retardation / diagnostic imaging
  • Fetal Growth Retardation / physiopathology*
  • Humans
  • Infant, Newborn
  • Pre-Eclampsia / diagnostic imaging
  • Pre-Eclampsia / physiopathology*
  • Pregnancy
  • Pregnancy, Twin
  • Remission, Spontaneous
  • Ultrasonography, Prenatal
  • Umbilical Arteries / diagnostic imaging
  • Umbilical Arteries / physiopathology*