Format

Send to

Choose Destination
Clin Pharmacol Ther. 2015 Sep;98(3):288-97. doi: 10.1002/cpt.166. Epub 2015 Jul 22.

Neonatal drug therapy: The first frontier of therapeutics for children.

Author information

1
Neonatal Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium.
2
Department of Development and Regeneration, KU, Leuven, Belgium.
3
Division of Pediatric Clinical Pharmacology, Children's National Health System, Washington, DC, USA.
4
Departments of Pediatrics, Integrative Systems Biology, Pharmacology and Physiology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
5
Intensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, the Netherlands.
6
Department of Paediatric Pharmacology, University Children's Hospital Basel, Basel, Switzerland.

Abstract

Knowledge about the safe and effective use of medicines in neonates has increased substantially but has resulted in few label changes. Drugs developed for use in adults are reshaped and tailored to specific neonatal indications. However, the use of drugs in neonates should not only mirror adult pharmacotherapy, but should be driven by their own specific needs. Therefore, building collaborative networks may assist to develop a newborn-driven research agenda addressing their clinical needs and diseases.

Comment in

PMID:
26095519
PMCID:
PMC4709252
DOI:
10.1002/cpt.166
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center