Real-time monitoring of mechanical changes during dynamic adhesion of erythrocytes to endothelial cells by QCM-D

Shaolian Zhang; Haihua Bai; Peihui Yang

doi:10.1039/c5cc03264d

Real-time monitoring of mechanical changes during dynamic adhesion of erythrocytes to endothelial cells by QCM-D

Chem Commun (Camb). 2015 Jul 21;51(57):11449-51. doi: 10.1039/c5cc03264d.

Authors

Shaolian Zhang¹, Haihua Bai, Peihui Yang

Affiliation

¹ Department of Chemistry, Jinan University, Guangzhou 510632, People's Republic of China. typh@jnu.edu.cn.

PMID: 26087999
DOI: 10.1039/c5cc03264d

Abstract

A quartz crystal microbalance with dissipation monitoring is used to measure changes in mechanical properties of diabetic red blood cells (RBCs) and normal RBCs. Moreover, the adhesion interaction between these two kinds of RBCs and endothelial cells (ECs) is further investigated using a proposed QCM-D biosensor for the first time.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomechanical Phenomena
Biosensing Techniques / instrumentation*
Cell Adhesion
Diabetes Mellitus, Type 2 / blood
Diabetes Mellitus, Type 2 / pathology
Elastic Modulus
Endothelial Cells / cytology*
Equipment Design
Erythrocyte Deformability
Erythrocytes / cytology*
Erythrocytes / pathology
Human Umbilical Vein Endothelial Cells
Humans
Quartz Crystal Microbalance Techniques / instrumentation*