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J Biomed Opt. 2015 Jun;20(6):066006. doi: 10.1117/1.JBO.20.6.066006.

Holographic laser Doppler imaging of pulsatile blood flow.

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Centre National de la Recherche Scientifique (CNRS) UMR 7587, Institut Langevin, Fondation Pierre-Gilles de Gennes, Institut National de la Santé et de la Recherche Médicale (INSERM) U 979, UPMC, Université Paris 7, Ecole Supérieure de Physique et de Chim.
Université de Picardie Jules Verne, INSERM U 1105, Paediatric Lung Function Laboratory, Amiens University Hospital, 80054 Amiens, France.


We report on wide-field imaging of pulsatile motion induced by blood flow using heterodyne holographic interferometry on the thumb of a healthy volunteer, in real time. Optical Doppler images were measured with green laser light by a frequency-shifted Mach-Zehnder interferometer in off-axis configuration. The recorded optical signal was linked to local instantaneous out-of-plane motion of the skin at velocities of a few hundreds of microns per second and compared to blood pulse monitored by plethysmoraphy during an occlusion-reperfusion experiment.

[Indexed for MEDLINE]

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