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Biol Trace Elem Res. 2016 Jan;169(1):41-5. doi: 10.1007/s12011-015-0401-9. Epub 2015 Jun 19.

Lead Assessment in Biological Samples of Children with Different Gastrointestinal Disorders.

Author information

1
Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad, 22060, Pakistan. shah_ceac@yahoo.com.
2
Department of Chemistry, Faculty of Science, Federal Urdu University of Arts, Science and Technology, Gulshan Campus, Karachi, Pakistan. shah_ceac@yahoo.com.
3
National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. naeemullah433@yahoo.com.
4
National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. tgkazi@yahoo.com.
5
Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad, 22060, Pakistan. ajmalkhan@ciit.net.pk.
6
Faculty of Allied Engineering and Technology, Dawood University of Engineering and Technology, Karachi, Pakistan. gakandhro@yahoo.com.
7
National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. hassanimranafridi@yahoo.com.
8
Chemistry Department, Abdul Wali Khan University, Mardan, Pakistan. bilal_ku2004@yahoo.com.
9
Department of Pharmacology, Faculty of Pharmacy, Federal Urdu University of Arts, Science and Technology, Gulshan Campus, Karachi, Pakistan. zahidphr@yahoo.com.
10
Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad, 22060, Pakistan. umarf@ciit.net.pk.

Abstract

Lead (Pb) levels have been evaluated in the biological samples of children with different gastrointestinal disorders. Blood, scalp hair, and urine samples of children (of age 4-10 years) complaining about different gastrointestinal disorders were analyzed. For comparison, age matched healthy subjects were also included in this study. Biological samples were digested in a microwave oven prior to Pb determination by graphite furnace atomic absorption spectrometry. Significant differences in Pb profile were found between the diseased and referent children. Elevated Pb contents were observed in case of diseased children than WHO permissible limit, while normal results were obtained for healthy referents. The results were compared with those of healthy children having the same age, socioeconomic status, and residential areas.

KEYWORDS:

Biological samples; Children; Gastrointestinal; Lead; Referents

PMID:
26085058
DOI:
10.1007/s12011-015-0401-9
[Indexed for MEDLINE]

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