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Immunity. 2015 Jun 16;42(6):979-81. doi: 10.1016/j.immuni.2015.06.001.

HGF Guides T Cells into the Heart.

Author information

1
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
2
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: klaus@liai.org.

Abstract

Expression of distinct homing receptors guides adaptive immune cells to antigen-rich tissue. In this issue of Immunity, Komarowska et al. (2015) describe an autocrine loop that is initiated by cardiac-expressed hepatocyte growth factor to direct T cells into the heart during inflammation and cardiac transplant rejection.

PMID:
26084015
DOI:
10.1016/j.immuni.2015.06.001
[Indexed for MEDLINE]
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