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Nat Rev Genet. 2015 Jul;16(7):373-4. doi: 10.1038/nrg3967. Epub 2015 Jun 16.

An ecosystem of cancer cell line factories to support a cancer dependency map.

Author information

1
Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.
2
1] Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA. [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA. [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA. [4] Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, Maryland 20815, USA.

Abstract

Jesse Boehm and Todd Golub call for an international effort to establish >10,000 cancer cell line models as a community resource. Cancer cell line factories will facilitate the creation of a cancer dependency map, connecting cancer genomics to therapeutic dependencies.

PMID:
26077369
DOI:
10.1038/nrg3967
[Indexed for MEDLINE]

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