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J Vet Med Sci. 2015 Nov;77(11):1545-8. doi: 10.1292/jvms.15-0030. Epub 2015 Jun 14.

Efficacy of five commercial disinfectants and one anionic surfactant against equine herpesvirus type 1.

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Epizootic Research Center, Equine Research Institute, Japan Racing Association,1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan.


We investigated the influences of various reaction conditions on equine herpesvirus type 1 (EHV-1) disinfection by 5 commercial disinfectants (3 quaternary ammonium compounds [QACs] and 2 chlorine-based disinfectants) and 1 anionic surfactant. QACs at their highest recommended concentrations had no virucidal effect on EHV-1 with a 10-min reaction time at 0°C or a 1-min reaction time at room temperature. Chlorine-based disinfectants achieved EHV-1 disinfection with a 10-min reaction time at -10°C or a 30-sec reaction time at room temperature. In the presence of 5% fetal bovine serum, QACs (except for benzalkonium chloride) showed more stable virucidal effects than did chlorine-based disinfectants. The virucidal effect of the anionic surfactant was almost equivalent to that of the QACs.

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