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J Neuropsychiatry Clin Neurosci. 2015 Summer;27(3):237-9. doi: 10.1176/appi.neuropsych.14030048. Epub 2015 Jun 12.

Preliminary Findings Supporting Insula Metabolic Activity as a Predictor of Outcome to Psychotherapy and Medication Treatments for Depression.

Author information

1
From the Dept. of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA (BWD, CLM, WEC, HSM); the Dept. of Biostatistics and Bioinformatics, Emory University School of Public Health, Atlanta, GA (MEK); and the Dept. of Psychology, Emory University, Atlanta, GA (WEC).

Abstract

A putative right anterior insula metabolism biomarker predictive of treatment outcomes was retrospectively applied to 30 depressed psychotherapy--or escitalopram-treated nonremitters who entered combination treatment. Patients whose added treatment matched the biomarker-indicated treatment remitted more often than biomarker-mismatched patients.

PMID:
26067435
PMCID:
PMC4788472
DOI:
10.1176/appi.neuropsych.14030048
[Indexed for MEDLINE]
Free PMC Article

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