Emerging developments in the use of bioactive glass for reconstruction of craniofacial bone

Br J Oral Maxillofac Surg. 2015 Oct;53(8):760-2. doi: 10.1016/j.bjoms.2015.04.019. Epub 2015 Jun 6.

Abstract

For decades, researchers have investigated the use of bioactive glasses as synthetic substitutes for bone grafts that can bond with bone, and recent discoveries have shown that their clinical performance in osteoplastic and reconstructive surgery has exceeded that of traditional synthetic materials. Craniofacial reconstructions with bioactive glass were associated with good functional and aesthetic results with no donor-site morbidity, and the material's unique ability to inhibit bacterial growth was advantageous when used in dead spaces that were chronically infected. Treatment of large defects in the head and neck with these multifunctional biomaterials is a suitable alternative to conventional methods.

Keywords: Alloplastic grafting materials; Bioactive glass; Osteoplastic and reconstructive surgery.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / therapeutic use*
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / therapeutic use*
  • Bone Substitutes / chemistry
  • Bone Substitutes / therapeutic use*
  • Bone Transplantation*
  • Composite Resins
  • Face / surgery*
  • Facial Bones / surgery*
  • Glass / chemistry
  • Humans
  • Plastic Surgery Procedures
  • Polymethyl Methacrylate
  • Skull / diagnostic imaging
  • Skull / surgery*
  • Wound Healing
  • Wound Infection / etiology
  • Wound Infection / prevention & control*

Substances

  • Anti-Infective Agents
  • Biocompatible Materials
  • Bone Substitutes
  • Composite Resins
  • Polymethyl Methacrylate