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Adv Mater. 2015 Jul 8;27(26):3901-8. doi: 10.1002/adma.201405660. Epub 2015 Jun 8.

Levitational Image Cytometry with Temporal Resolution.

Author information

1
Department of Radiology, Stanford School of Medicine, Demirci Bio-acoustic MEMS in Medicine (BAMM) Labs, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA, 94304, USA.
2
Demirci BAMM Labs, Divisions of Biomedical Engineering Infectious Diseases, and Renal Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
3
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.
4
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.

Abstract

A simple, yet powerful magnetic-levitation-based device is reported for real-time, label-free separation, as well as high-resolution monitoring of cell populations based on their unique magnetic and density signatures. This method allows a wide variety of cellular processes to be studied, accompanied by transient or permanent changes in cells' fundamental characteristics as a biological material.

KEYWORDS:

biological materials; cell screening; cell separation; cells; magnetic levitation

PMID:
26058598
PMCID:
PMC4631436
DOI:
10.1002/adma.201405660
[Indexed for MEDLINE]
Free PMC Article

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