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Cell. 2015 Jun 4;161(6):1246-8. doi: 10.1016/j.cell.2015.05.043.

Dying mRNA Tells a Story of Its Life.

Author information

1
Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: ewallace@uchicago.edu.
2
Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: dadrummond@uchicago.edu.

Abstract

In this issue of Cell, Pelechano et al. report that sequencing of mRNA decay intermediates shows surprisingly tight coupling of a major decay pathway to the movement of the last translating ribosome, revealing stress- and starvation-dependent modulation of translation elongation.

PMID:
26046434
DOI:
10.1016/j.cell.2015.05.043
[Indexed for MEDLINE]
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