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Arch Pharm (Weinheim). 1989 Aug;322(8):499-505.

[Synthesis of racemates and enantiomers of 3-alkylthalidomide analogs and determination of their absolute configuration].

[Article in German]


The syntheses of the racemates and the enantiomers of the title compounds 7a-7c and of racem. 1,3-dimethyl-thalidomide (8) are reported. The absolute configuration of the optically active products is determined. The hypnotic activities of the analogs of thalidomide 7a - 7c and of the intermediates 6a - 6c are to be tested in animals.

[Indexed for MEDLINE]

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