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Curr Opin Chem Biol. 2015 Aug;27:10-7. doi: 10.1016/j.cbpa.2015.05.001. Epub 2015 May 29.

Emerging fluorescent protein technologies.

Author information

1
Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
2
Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada. Electronic address: robert.e.campbell@ualberta.ca.

Abstract

Fluorescent proteins (FPs), such as the Aequorea jellyfish green FP (GFP), are firmly established as fundamental tools that enable a wide variety of biological studies. Specifically, FPs can serve as versatile genetically encoded markers for tracking proteins, organelles, or whole cells, and as the basis for construction of biosensors that can be used to visualize a growing array of biochemical events in cells and tissues. In this review we will focus on emerging applications of FPs that represent unprecedented new directions for the field. These emerging applications include new strategies for using FPs in biosensing applications, and innovative ways of using FPs to manipulate protein function or gene expression.

PMID:
26043278
DOI:
10.1016/j.cbpa.2015.05.001
[Indexed for MEDLINE]

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