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J Neuropsychiatry Clin Neurosci. 2014 Fall;26(4):382-5. doi: 10.1176/appi.neuropsych.13090204.

Decreased dopamine concentrations in the frontal cortex after ablative surgeries in patients exhibiting self-injurious behavior: a microdialysis study.

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From the Dept. of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Haidian, Beijing, China (AL, HZ, ZZ); and the Dept. of Neurosurgery, PLA General Hospital, Hainan Campus, Haikou, Hainan, China.


The authors examined brain neurochemistry in four patients with mental retardation with self-injurious behaviors after ablative surgeries. The authors found that surgeries in the human limbic system can alter dopamine levels in the frontal cortex over a 36-hour period.

[Indexed for MEDLINE]

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