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Open Forum Infect Dis. 2015 Feb 4;2(1):ofv004. doi: 10.1093/ofid/ofv004. eCollection 2015 Jan.

Weight gain after fecal microbiota transplantation.

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Department of Internal Medicine , Newport Hospital.
Division of Gastroenterology, Center for Women's Gastrointestinal Medicine at the Women's Medicine Collaborative , The Miriam Hospital, Warren Alpert School of Brown University , Providence, Rhode Island.


Fecal microbiota transplantation (FMT) is a promising treatment for recurrent Clostridium difficile infection. We report a case of a woman successfully treated with FMT who developed new-onset obesity after receiving stool from a healthy but overweight donor. This case may stimulate further studies on the mechanisms of the nutritional-neural-microbiota axis and reports of outcomes in patients who have used nonideal donors for FMT.


Clostridium difficile infection; fecal microbiota transplantation; gut microbiota; obesity

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