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Presse Med. 2015 Jun;44(6 Pt 1):631-8. doi: 10.1016/j.lpm.2015.04.011. Epub 2015 May 29.

[Syphilis and pregnancy].

[Article in French]

Author information

1
Assistance publique-Hôpitaux de Paris, université Paris Descartes Sorbonne Paris Cité, hôpital Necker-Enfants-Malades, service de maladies infectieuses et tropicales, 75015 Paris, France; Institut Pasteur, centre national de référence Listeria, centre collaborateur OMS Listeria, unité de biologie des infections, Inserm U1117, 75013 Paris, France. Electronic address: caroline.charlier@nck.aphp.fr.
2
Assistance publique-Hôpitaux de Paris, université Paris Descartes Sorbonne Paris Cité, hôpital Cochin Port Royal, centre national de référence syphilis, 75014 Paris, France.

Abstract

Syphilis is a sexually transmitted disease responsible for a congenital severe infection. Congenital syphilis is complicated by fetal loss/neonatal death (50%), prematurity (25%) and major long term sequelae in other surviving children (20%). Every woman delivering a stillborn after 20WG should be tested for syphilis. Early screening is the cornerstone of prevention, and should be repeated in women at higher risk of contamination. Maternal management relies on early benzathine penicillin administration. Neonatal management relies on early diagnosis and prompt adequate penicillin therapy.

PMID:
26033558
DOI:
10.1016/j.lpm.2015.04.011
[Indexed for MEDLINE]

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