Format

Send to

Choose Destination
Pediatr Allergy Immunol. 2015 Sep;26(6):522-9. doi: 10.1111/pai.12415. Epub 2015 Jul 22.

Validation of a Comprehensive Early Childhood Allergy Questionnaire.

Author information

1
Sydney Medical School Nepean, The University of Sydney, Sydney, NSW, Australia.
2
Department of Paediatrics, Blue Mountains ANZAC Memorial Hospital, Katoomba, NSW, Australia.
3
Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, NSW, Australia.

Abstract

BACKGROUND:

Parental questionnaires to assess incidence of pediatric allergic disease have been validated for use in school-aged children. Currently, there is no validated questionnaire-based assessment of food allergy, atopic dermatitis (AD), and asthma for infants and young children.

METHODS:

The Comprehensive Early Childhood Allergy Questionnaire was designed for detecting AD, asthma, and IgE-mediated food allergies in children aged 1-5 years. A nested case-control design was applied. Parents of 150 children attending pediatric outpatient clinics completed the questionnaire before being clinically assessed by a pediatrician for allergies. Sensitivity, specificity, and reproducibility of the questionnaire were assessed.

RESULTS:

Seventy-seven children were diagnosed with one or more current allergic diseases. The questionnaire demonstrated high overall sensitivity of 0.93 (95% CI 0.86-0.98) with a specificity of 0.79 (95% CI 0.68-0.88). Questionnaire reproducibility was good with a kappa agreement rate for symptom-related questions of 0.45-0.90.

CONCLUSIONS:

Comprehensive Early Childhood Allergy Questionnaire accurately and reliably reflects the presence of allergies in children aged 1-5 years. Its use is warranted as a tool for determining prevalence of allergies in this pediatric age group.

KEYWORDS:

asthma; atopic dermatitis; childhood allergy; food allergy; parental questionnaire validation

PMID:
26031325
DOI:
10.1111/pai.12415
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center